In the shadow of the Covid-19 pandemic, the number of overdose deaths surged past 100,000 for the first time in 2021.

Patrick Radden Keefe’s new book provides the fullest accounting so far of Purdue Pharma’s role in the opioid crisis.

This portrait of the privileged scion as a crack addict helps explain his father’s odd appeal.

In “Transcendent Kingdom,” a young Black woman refuses to be defined by other people’s narratives.

During a summer of uprising and mutual aid, Nadine Little moved from park underpasses to hotels and back again. She’s not alone.

A philosopher, a medical crisis, and a mystery

Michael Fox had no choice but to give Scott Wharton life without parole—then spent years fighting to set him free. This is a real-life parable about our broken criminal justice system.

What neuroscience tells us about the persistence of hatred

When Chad Baker died from a lethal combination of cocaine and heroin, prosecutors charged Tommy Kosto, his friend and fellow drug user, with killing him—a tactic from the Reagan-era war on drugs that is gaining popularity around the country and making today's opioid crisis even worse.

How the 12 Step program and its decades-old philosophy are exacerbating the opioid crisis

How concerns about the social-media platform's targeting of younger users apply to everything it does

Twenty years ago, scoring political points with personal tales of drug-addicted relatives would have been frowned upon. Now, everybody from Donald Trump to Jeb Bush is doing it.

Addiction wasn't incidental to his talent: It was its essence

I decided to bet on the sport I love. I lost, even when I won.

The dogma of AA has taken over